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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT3
All Species:
31.82
Human Site:
T516
Identified Species:
87.5
UniProt:
P40763
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40763
NP_003141.2
770
88068
T516
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Chimpanzee
Pan troglodytes
XP_511505
786
90098
T513
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849765
770
88039
T516
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Cat
Felis silvestris
Mouse
Mus musculus
P42227
770
88035
T516
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Rat
Rattus norvegicus
P52631
770
88021
T516
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6DV79
771
88152
T516
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Frog
Xenopus laevis
Q9PVX8
769
87956
T516
S
W
Q
F
S
S
T
T
K
R
G
L
S
I
E
Zebra Danio
Brachydanio rerio
NP_571554
806
92133
T517
S
W
Q
F
S
S
T
T
K
R
G
L
T
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24151
761
86396
P490
I
V
H
G
N
Q
E
P
Q
S
W
A
T
I
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
N.A.
99.4
N.A.
99.8
99.7
N.A.
N.A.
97.5
95.8
83.2
N.A.
22.9
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
N.A.
99.8
N.A.
100
100
N.A.
N.A.
98.4
97.7
88.2
N.A.
40.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
89
% E
% Phe:
0
0
0
89
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
89
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% I
% Lys:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
89
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
89
0
0
12
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
89
0
0
0
0
0
% R
% Ser:
89
0
0
0
89
89
0
0
0
12
0
0
78
0
0
% S
% Thr:
0
0
0
0
0
0
89
89
0
0
0
0
23
0
12
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
89
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _